Estonian Genome Centre

Contacts of UT units

Dean's Office

Faculty contacts link:
Employee contacts

Faculty phone:
+ 372 737 5341

Faculty email:
hv.dekanaat [at] ut.ee

Faculty address:
Jakobi 2, rooms 116–121, 51005 Tartu
Institute of History and Archaeology

Faculty link:
www.flaj.ut.ee

Faculty contacts link:
Employee contacts

Faculty phone:
+372 737 5651

Faculty address:
Jakobi 2, 51005 Tartu
Institute of Estonian and General Linguistics

Faculty link:
keel.ut.ee

Faculty contacts link:
Employee contacts

Faculty phone:
+372 737 5221

Faculty email:
keeleteadus [at] ut.ee

Faculty address:
Jakobi 2, 51005 Tartu
Institute of Philosophy and Semiotics

Faculty link:
www.flfi.ut.ee

Faculty contacts link:
Employee contacts

Faculty phone:
+372 737 5314

Faculty email:
filosoofia.semiootika [at] ut.ee

Faculty address:
Jakobi 2, rooms 309–352, 51005 Tartu
Institute of Cultural Research

Faculty link:
www.flku.ut.ee

Faculty contacts link:
Employee contacts

Faculty phone:
(+372) 737 5223

Faculty email:
kultuuriteadused [at] ut.ee

Faculty address:
Ülikooli 16, 51003 Tartu
School of Theology and Religious Studies

Faculty link:
us.ut.ee

Faculty contacts link:
Employee contacts

Faculty phone:
+372 737 5301

Faculty email:
us [at] ut.ee

Faculty address:
Ülikooli 18–310, 50090 Tartu
College of Foreign Languages and Cultures

Faculty link:
maailmakeeled.ut.ee

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Employee contacts

Faculty email:
keeled [at] ut.ee

Faculty address:
J. Liivi 4, 50409, Tartu
Viljandi Culture Academy

Faculty link:
kultuur.ut.ee

Faculty contacts link:
Employee contacts

Faculty phone:
+372 435 5232

Faculty email:
kultuur [at] ut.ee

Faculty address:
Posti 1, 71004 Viljandi

Dean's Office

Faculty contacts link:
Employee contacts

Faculty phone:
+ 372 737 5900

Faculty email:
sotsiaalteadused [at] ut.ee

Faculty address:
Lossi 36, 51003 Tartu
Institute of Education

Faculty link:
www.ht.ut.ee

Faculty contacts link:
Employee contacts

Faculty phone:
+372 737 6440

Faculty email:
haridus [at] ut.ee

Faculty address:
Salme 1a–29, 50103 Tartu
Johan Skytte Institute of Political Studies

Faculty link:
skytte.ut.ee

Faculty contacts link:
Employee contacts

Faculty phone:
+372 737 5582

Faculty email:
skytte [at] ut.ee

Faculty address:
Lossi 36–301, 51003 Tartu
School of Economics and Business Administration

Faculty link:
majandus.ut.ee

Faculty contacts link:
Employee contacts

Faculty phone:
+372 737 6310

Faculty email:
majandus [at] ut.ee

Faculty address:
Narva mnt 18, 51009 Tartu
Institute of Psychology

Faculty link:
psychology.ut.ee

Faculty contacts link:
Employee contacts

Faculty phone:
+372 737 5902

Faculty email:
psyhholoogia [at] ut.ee

Faculty address:
Näituse 2, 50409 Tartu
School of Law

Faculty link:
law.ut.ee

Faculty contacts link:
Employee contacts

Faculty phone:
+372 737 5390

Faculty email:
oi [at] ut.ee

Faculty address:
Näituse 20–324, 50409 Tartu
Institute of Social Studies

Faculty link:
yti.ut.ee

Faculty contacts link:
Employee contacts

Faculty phone:
+372 737 5188

Faculty email:
yhiskonnateadused [at] ut.ee

Faculty address:
Lossi 36, 51003 Tartu
Narva College

Faculty link:
www.narva.ut.ee

Faculty contacts link:
Employee contacts

Faculty phone:
+372 740 1900

Faculty email:
college [at] narva.ut.ee

Faculty address:
Raekoja plats 2, 20307 Narva
Pärnu College

Faculty link:
www.pc.ut.ee

Faculty contacts link:
Employee contacts

Faculty phone:
+372 445 0520

Faculty email:
info [at] pc.ut.ee

Faculty address:
Ringi 35, 80012 Pärnu

Dean's Office

Faculty contacts link:
Employee contacts

Faculty phone:
+372 737 5326

Faculty email:
med [at] ut.ee

Faculty address:
Ravila 19, 50411 Tartu
Institute of Biomedicine and Translational Medicine

Faculty link:
biomeditsiin.ut.ee

Faculty contacts link:
Employee contacts

Faculty phone:
+372 737 4210

Faculty email:
bsmi [at] ut.ee

Faculty address:
Biomeedikum, Ravila 19, 50411 Tartu
Institute of Pharmacy

Faculty link:
farmaatsia.ut.ee

Faculty contacts link:
Employee contacts

Faculty phone:
+372 737 5286

Faculty email:
pharmacy [at] ut.ee

Faculty address:
Nooruse 1, 50411 Tartu
Institute of Dentistry

Faculty link:
hambaarstiteadus.ut.ee

Faculty contacts link:
Employee contacts

Faculty phone:
+372 731 9856

Faculty address:
Raekoja plats 6, 51003 Tartu
Institute of Clinical Medicine

Faculty link:
clinicalmedicine.ut.ee

Faculty contacts link:
Employee contacts

Faculty phone:
+372 737 5323

Faculty email:
kmi [at] ut.ee

Faculty address:
L. Puusepa 8, 50406 Tartu
Institute of Family Medicine and Public Health

Faculty link:
tervis.ut.ee

Faculty contacts link:
Employee contacts

Faculty phone:
+372 737 4190

Faculty email:
dph [at] ut.ee

Faculty address:
Ravila 19, 50411 Tartu
Institute of Sport Sciences and Physiotherapy

Faculty link:
www.kk.ut.ee

Faculty contacts link:
Employee contacts

Faculty phone:
+372 737 5360

Faculty email:
kkdek [at] ut.ee

Faculty address:
Jakobi 5–205, 51005 Tartu

Dean's Office

Faculty contacts link:
Employee contacts

Faculty phone:
+372 737 5820

Faculty email:
ltt [at] ut.ee

Faculty address:
Vanemuise 46–208, 51003 Tartu
Institute of Computer Science

Faculty link:
cs.ut.ee

Faculty contacts link:
Employee contacts

Faculty phone:
+372 737 5445

Faculty email:
ics [at] ut.ee

Faculty address:
Narva mnt 18, 51009 Tartu
Estonian Marine Institute

Faculty link:
mereinstituut.ut.ee

Faculty contacts link:
Employee contacts

Faculty phone:
+372 671 8902

Faculty address:
Mäealuse 14, 12618 Tallinn
Institute of Physics

Faculty link:
www.fi.ut.ee

Faculty contacts link:
Employee contacts

Faculty address:
W. Ostwaldi 1, 50411 Tartu
Institute of Chemistry

Faculty link:
chem.ut.ee

Faculty contacts link:
Employee contacts

Faculty phone:
+372 737 5261

Faculty email:
chemistry [at] ut.ee

Faculty address:
Ravila 14a, 50411 Tartu
Institute of Genomics

Faculty link:
genomics.ut.ee

Faculty contacts link:
Employee contacts

Faculty phone:
+372 737 4000

Faculty email:
egv [at] ut.ee

Faculty address:
Riia 23b, 51010 Tartu
Institute of Mathematics and Statistics

Faculty link:
www.math.ut.ee

Faculty contacts link:
Employee contacts

Faculty phone:
+372 737 5860

Faculty email:
ltms [at] ut.ee

Faculty address:
Narva mnt 18, 51009 Tartu
Institute of Molecular and Cell Biology

Faculty link:
tymri.ut.ee

Faculty contacts link:
Employee contacts

Faculty phone:
+372 737 5027

Faculty address:
Riia 23, 23b–134, 51010 Tartu
Tartu Observatory

Faculty link:
www.kosmos.ut.ee

Faculty contacts link:
Employee contacts

Faculty phone:
+372 737 4510

Faculty email:
kosmos [at] ut.ee

Faculty address:
Observatooriumi 1, Tõravere, 61602 Tartumaa
Institute of Technology

Faculty link:
tuit.ut.ee

Faculty contacts link:
Employee contacts

Faculty phone:
+372 737 4800

Faculty email:
info [at] tuit.ut.ee

Faculty address:
Nooruse 1, 50411 Tartu
Institute of Ecology and Earth Sciences

Faculty link:
www.omi.ut.ee

Faculty contacts link:
Employee contacts

Faculty phone:
+372 737 5835

Faculty email:
om [at] ut.ee

Faculty address:
Vanemuise 46, 51003 Tartu

Institutions

Library

Faculty link:
utlib.ut.ee

Faculty contacts link:
Employee contacts

Faculty phone:
+372 737 5702

Faculty email:
library [at] utlib.ee

Faculty address:
W. Struve 1, 50091 Tartu
Youth Academy

Faculty link:
teaduskool.ut.ee

Faculty contacts link:
Employee contacts

Faculty phone:
+372 737 5581

Faculty email:
teaduskool [at] ut.ee

Faculty address:
Uppsala 10, 51003 Tartu
Museum

Faculty link:
muuseum.ut.ee

Faculty contacts link:
Employee contacts

Faculty phone:
+372 737 5674

Faculty email:
muuseum [at] ut.ee

Faculty address:
Lossi 25, 51003 Tartu
University of Tartu Natural History Museum and Botanical Garden

Faculty link:
natmuseum.ut.ee

Faculty contacts link:
https://www.ut.ee/en/kontakt/loodusmuuseum-botaanikaaed

Faculty phone:
+372 737 6076

Faculty email:
loodusmuuseum [at] ut.ee

Faculty address:
Vanemuise 46, 51003 Tartu

Support Units

Administrative Office

Faculty contacts link:
Employee contacts

Faculty phone:
+372 737 5606

Faculty email:
kantselei [at] ut.ee

Faculty address:
Ülikooli 18a, 51005 Tartu
Centre for Entrepreneurship and Innovation

Faculty contacts link:
Employee contacts

Faculty phone:
+372 737 4809

Faculty email:
eik [at] ut.ee

Faculty address:
Narva mnt 18, 51009, Tartu
University Office in Tallinn

Faculty link:
University Office in Tallinn

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Employeescontacts

Faculty phone:
+372 737 6600

Faculty email:
esindus [at] tallinn.ut.ee

Faculty address:
Teatri väljak 3, 10143 Tallinn
Estates Office

Faculty contacts link:
Employee contacts

Faculty phone:
+372 737 5137

Faculty address:
Ülikooli 18a, 51005 Tartu
Finance Office

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Employee contacts

Faculty phone:
+372 737 5125

Faculty email:
rahandus [at] ut.ee

Faculty address:
Jakobi 4, 51005 Tartu
Grant Office

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Employee contacts

Faculty phone:
+372 737 6215

Faculty address:
Raekoja plats 9, 51004 Tartu
Information Technology Office

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Employee contacts

Faculty phone:
+372 737 6000, IT-help: +372 737 5500

Faculty email:
ito [at] ut.ee, arvutiabi [at] ut.ee

Faculty address:
Ülikooli 18a, 51005 Tartu
Human Resources Office

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Employee contacts

Faculty phone:
+372 737 5145

Faculty email:
personal [at] ut.ee

Faculty address:
Ülikooli 18, rooms 302 and 304, 50090 Tartu
Internal Audit Office

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Employee contacts

Faculty email:
siseaudit [at] ut.ee

Faculty address:
Ülikooli 18-244, 51005 Tartu
International Cooperation and Protocol Office

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Employee contacts

Faculty phone:
+372 737 6123

Faculty email:
iro [at] ut.ee

Faculty address:
Ülikooli 18, rooms 104, 301, 305, 50090 Tartu
Marketing and Communication Office

Faculty contacts link:
Employee contacts

Faculty phone:
+372 737 5687

Faculty email:
info [at] ut.ee, avalik [at] ut.ee

Faculty address:
Ülikooli 18, rooms 102, 104, 209, 210, 50090 Tartu
Office of Academic Affairs

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Employee contacts

Faculty phone:
+372 737 5620

Faculty address:
Ülikooli 18, 50090 Tartu
Procurement Office

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Employee contacts

Faculty phone:
+372 737 6632

Faculty email:
tuuli.ilula [at] ut.ee

Faculty address:
Ülikooli 18a, 51005 Tartu
Rector's Office
Rector's Strategy Office

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Employee contacts

Faculty phone:
+372 737 5600

Faculty email:
rektor [at] ut.ee

Faculty address:
Ülikooli 18, 50090 Tartu
Student Council

Faculty link:
tyye.ut.ee

Faculty contacts link:
Employee contacts

Faculty email:
info [at] tyye.ee

Faculty address:
Ülikooli 18b, 51005 Tartu
University of Tartu Press

Faculty link:
www.tyk.ee

Faculty contacts link:
Employee contacts

Faculty phone:
+372 737 5945

Faculty email:
tyk [at] ut.ee

Faculty address:
W. Struve 1, 50091 Tartu

University of Tartu Academic Sports Club

Faculty link:
sport.ut.ee

Faculty phone:
+372 737 5371

Faculty email:
info [at] tysk.ee

Faculty address:
Ujula 4, 51008 Tartu
Tartu Student Village

Faculty link:
campus.ee

Faculty phone:
+372 740 9959

Faculty email:
info [at] kyla.ee

Faculty address:
Narva mnt 25, 51013 Tartu
Tartu Students’ Club

Faculty link:
www.tym.ee

Faculty phone:
+372 730 2400

Faculty email:
tym [at] ut.ee

Faculty address:
Kalevi 24, 51010 Tartu
Tartu University Hospital

Faculty link:
www.kliinikum.ee/eng

Faculty email:
kliinikum [at] kliinikum.ee

Faculty address:
L. Puusepa 1a, 50406 Tartu
University of Tartu Foundation

Faculty link:
sihtasutus.ut.ee/en

Faculty phone:
+372 737 5852

Faculty email:
triin.vakker [at] ut.ee

Faculty address:
Ülikooli 18, 50090 Tartu
View all other units

Faculty link:
www.ut.ee/en/other-units

Functional genomics, or the effect of DNA sequence variants on quantitative trait variability and disease risk expression in the population, has made EGC one of the most studied biobanks in the world, with EGC researchers participating in the work of numerous international consortiums and contributed to the discovery of more than 35,000 (65%) of the genetic variants associated with complex characteristics.

As new fields of research, EGC has successfully launched systems biology, microbiome and pharmacogenetics, bringing to Estonia experts with an international background. The research at EGC directly supports the activities of the Estonian National Personalized Medicine Program, both with the development of polygenic risk scores and with the improvement of genotyping chip data. As new directions we see multi-level analysis of the health trajectories of biobank participants, analysis of molecular profiles at DNA, RNA, proteins, metabolites and cellular traits level, and hypothesis-free data mining using machine learning and AI techniques.

The head of the Estonian Genome Centre is Vice Director, Professor of Epi- and Pharmacogenomics Dr. Lili Milani (lili.milani [ät] ut.ee).

Research group of pharmacogenetics

Despite recent advances in pharmacogenomic research, interindividual variability in drug metabolism and sensitivity for drug toxicity persists as a major problem for drug treatment. Recent research has highlighted the large extent of rare variant in genes with importance for drug metabolism. The aim of this work is to discover and investigate the effect of common and rare genetic variants related to suboptimal drug metabolism and adverse drug reactions (ADRs) in the Estonian and other European populations. This will be achieved by using genome sequences of 5000 and genotype data of 200,000 individuals combined with extensive health records regarding drug prescriptions and ADR diagnoses. The identified gene-ADR associations will be tested using functional studies. The results will serve as a basis for variants that can be included for preemptive pharmacogenomic testing, which could ultimately reduce the health and economic burden of low drug efficacy and unnecessary side effects caused by genetic variants.
The research group of pharmacogenetics is lead by Professor Dr. Lili Milani, lili.milani [ät] ut.ee

Research group of metabolomics and systems

Studies the interactios between the genome and metabolome with regard to human diseases. This includes work with metabolomics data sets collected with NMR and mass-spectrometry. We search for associations between genomic markers and metabolite levels as well as more complicated patterns in these data sets with the intent to understand and predict common diseases. This work requires creating new bioinformatics algorithms, scripts and tools (C++, Phython) as well as conducting high pergormance cluster computations.
The research group of metabolomics and systems is lead by Associate Professor Dr. Toomas Haller, toomas.haller [ät] ut.ee

Research group of mRNA

It is known that the genome apparently healthy individuals acutally harbors dozens of gene-disrupting variants (predicted to results in loss of function at the protein level). On the other hand, many phenotypic traits show inconsistent inheritance patterns due to penetrance and expressivity. The very first readout of genomic information is RNA, where celss have evolved several quality control mechanisms to minimize the impact of potentially harmful mutations. Our aim is to understand how mRNA regulation contributes to the buffering of such deleterious genetic variants.
The research group of mRNA is lead by Associate Professor Dr. Tarmo Annilo, tarmo.annilo [ät] ut.ee

Research group of microbiome

The human intestinal tract is colonized by thousands of different species of microorganisms, collectively called the microbiota. The gut microbiome (collection of all microbial genes) encodes much more genes than the human genome and provides us with numerous complementary functions. The microbioal community has a critical role in many aspects of health, including immunit and metabolism. Our group addresses questions about the relationships between microbiome and human host, where we currently focus on two major ares: 1) we explore the host-microbiome interactions in development of type 2 diabetes and 2) elucidate the direct and indirect mechanisms through which the human microbiome shapes the efficacy and toxicity of commonly used drugs.
The research group of microbiome is lead by Associate Professor Dr. Elin Org, elin.org [ät] ut.ee

Research group of functional genomics

Research group of functional genomics is focused on understanding the molecular function of human genome variation. The group's broader scientific interest lies in understanding the genetic architecture of complex human phenotypes, focusing on intermediate molecular measurements (such as levels of gene expression in human tissues, cellular fractions and circulating small molecules) and human stature to estimate the role of both rare and common genetic variation of phenotypic outcomes through various models of inheritance (additive, recessive, epistatic and epigenetic). We implement a range of bioinformatics and genetic epidemiology techniques to map endophenotypes quantitive trait loci (QTL) and to annotate known disease associations with downstream molecular mechanisms.
The research group of functional genomics is lead by vice director, Professor Dr. Tõnu Esko, tonu.esko [ät] ut.ee

Research group of bioinformatics

The bioinformatics research group handles the quality control and processing of multi-omics data and offers general bioinformatics support for all research groups within the Genome Centre. Method development plays an important role in the scientific activities of the group, including software for genome-wide association studies (GWAMA, MR-MEGA, SCOPA), as well as novel solutions for DNA copy number variant detection and analysis. In addition, the members of the group are involved in projects studying the genetic background of different traits and diseases related to metabolic health and female reproductive health.

The research group of functional genomics is lead by Professor Dr. Reedik Mägi, reedik.magi [ät] ut.ee

Research group of neuropsychiatric genomics

Mental health problems are extremely prevalent in the modern societies, with everysecond individual affected during their lifetime. However, the causal mechanisms ofsuch problems are not well understood. This is hindering advancements in novel prevention and treatment strategies to improve the quality of life of affected individuals and their family members. Our research team aims to advance the understanding of the causes and consequences of mental health problems across the lifespan and move towards better and personalized prevention and treatment strategies.

Our group is currently mainly working on two larger themes:

Exploring the genetic and environmental factors (as well as their interplay) influencing the onset, course and outcomes of neuropsychiatric disorders andrelated traits. We are currently focusing specifically on mood and anxiety disorders, attention deficit/hyperactivity disorder, Alzheimer’s disease and other dementias.
Investigating the mechanisms underlying the strong comorbidity between psychiatric disorders and somatic diseases, such as cardiovascular disease, type 2 diabetes, asthma and COVID-19 severity, to improve disease management and health outcomes of the patients.

The research group of neuropsychiatric genomics is led by Associate Professor Dr. Kelli Lehto, kelli.lehto [ät] ut.ee

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Estonian Genome Centre